Overcoming Fear in Biotech Investing: How to Thrive Amid Volatility

To Physicians and Investors,

Biotech investing is not for the faint of heart. The sector’s volatility, driven by market sentiment, regulatory shifts, or macroeconomic events like the tariff concerns earlier this year, can test even the most seasoned investors. In early April, as fears of tariffs roiled the markets, benchmarks like the Dow, S&P 500, and Nasdaq Biotech Index (NBI) took significant hits. Biotech stocks, often more sensitive to sentiment, were hit particularly hard.

During such times, the temptation to sell and move to cash can be overwhelming. Conventional wisdom screams, “Protect your gains!” But as we know, conventional wisdom is often wrong. In moments of volatility, the best course is to stay patient—or better yet, average down on fundamentally strong companies. The challenge isn’t knowing what to do; it’s executing it in the face of our greatest nemesis: FEAR.

Fear: The Silent Saboteur

Fear is a powerful emotion, capable of derailing even the most intelligent investors. As physicians, your above-average intellect is a double-edged sword. While it equips you to analyze complex biotech opportunities, it can also amplify fear, leading to impulsive decisions you later regret. The antidote? Surrounding yourself with mentors and peers who can help you see fear for what it is: False Expectations Appearing Real.

Let me share a personal story from this year’s market turbulence.

A Lesson in Courage

At Evergrowth, our annual meeting in late March coincided with the onset of a worsening market crash in April. The pressure to sell profitable positions and “protect gains” was intense. Succumbing to fear, I moved to a high cash position—over 50% of our portfolio—rationalizing it as prudence. But deep down, I knew this was fear, not strategy.

Reflecting on my 1.5 years as a biotech consultant and the success of our investment approach, I realized I was deviating from what had always worked: trusting our research and staying the course. A trusted colleague, a registered investment advisor managing over $200M and a long-time collaborator, reinforced this. Together, we’ve analyzed countless biotech stocks, and his encouragement to double down on our fundamentally strong holdings was the push I needed.

I acted decisively. I redeployed nearly 100% of our cash, repurchasing sold shares and adding to our strongest positions. One such position was a “Mystery Stock” in telemedicine, and another was “Mystery Stock H” (MSH), a biotech with robust sales growth in its lead drug for hereditary angioedema. Despite MSH’s underperformance at the time, its fundamentals—strong sales, label expansion, and a promising pipeline—made it a compelling growth and value play. Keep in mind these are real stock but I named them Mystery Stock for compliance reasons.

The Payoff

Two months later, the results speak for themselves. Our portfolio’s gross returns surged from 27% since inception to 63.37% as of this writing.

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Our $152,000 investment in the telemedicine stock grew to $291,705, a 92.2% gain. MSH, where we invested $200,000, climbed to $309,780, delivering a 54.2% unrealized gain. These outcomes reaffirm the power of staying true to our principles, inspired by Warren Buffett’s wisdom: “Be greedy when others are fearful.”

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Your Path to Wealth

As physicians, your expertise in medicine gives you a unique edge in biotech investing. But intelligence alone isn’t enough—conquering fear is the key to market-beating returns. By surrounding yourself with bold mentors and peers, you can shield yourself from volatility’s emotional toll and leverage your knowledge to build wealth.

If you’re a physician looking to harness biotech investing to double your money every three to four years and secure a luxurious, early retirement, let’s connect. Send me a message, and we’ll discuss how Evergrowth’s disciplined approach can work for you.

To your success,

Dr. Harvey Tran

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You pour countless hours into your clinic or hospital, saving lives but often sacrificing your own—your health, your family, your freedom. You’re trading precious time for dollars, with little left for travel or the life you want.

Allow me to ask you the following questions:

  • Would more time and money let you live better?
  • What if you could change that?
  • What if you leveraged your medical expertise to make your hard-earned dollars grow through smart investing?
  • Would working smarter, not harder, transform your life?
  • How about having a voice in investments that grow your wealth and help your patients?

If any of these hit home, our biotech hedge fund (Evergrowth BioHealthcare Capital)—designed by doctors, for doctors—might be your answer. Here’s what you’d gain by joining us:

  • Invest in what you know, using your clinical edge.
  • Grow your wealth into generational riches for you and your kids.
  • Work fewer hours as your investments take off.
  • Retire early to travel and live more.
  • Prioritize your health and happiness.
  • Connect with other physician investors.
  • Support innovations that bring hope to patients on a massive scale.
  • Become a Medical Advisor (just one hour a month commitment).
  • We only get a small share of your profits, if and only if, we can beat the 8% average stock market performance for you.

Disclaimer: This blog is for educational and informational purposes only. It’s not a recommendation to buy, sell, or hold any stock. Always consult your investment advisor and do your due diligence before investing. In working smarter rather than harder, I wrote an initial draft based on my knowledge, experience, and insight. I then leverage AI to put the information together into this presentable format.

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